Aparna Keshaviah

Aparna Keshaviah

Senior Statistician
  • Statistical modeling
  • Data visualization
  • Survey design
  • Quality control 
Focus Areas
  • Health
  • Population Health
  • Nutrition
  • Opioids
  • Human Services
About Aparna

Aparna Keshaviah is an applied statistician who works at the developmental cusp of emerging public health topics. She has almost two decades of experience leading the design and analysis of randomized controlled trials to evaluate health treatments and screening approaches. Her research is transdisciplinary in nature, spanning the fields of public health, medicine, environmental health, social science, and the humanities.

At Mathematica, Keshaviah has been at the forefront of bringing innovative data sources, advanced analytics, and visualization tools to health policy research. She led a highly visible symposium to explore the real-world potential of wastewater testing to support decision making around the opioid epidemic. Her insights into the practical applications of the methodology have been highly sought after. She currently works with several states to develop wastewater pilot studies, is an expert reviewer for grant programs focused on translational research, and conducted numerous briefings for Congress, Food and Drug Administration, National Institute on Drug Abuse, and state and community stakeholders. She also designed a dynamic dashboard (S.T.Op NextGen) to help health care providers understand and assess the unique health risks faced by women of childbearing age who misuse opioids. Beyond her work on the opioid epidemic, Keshaviah studies pharmaceutical drug development and safety, the economic impacts of legalizing marijuana, and the health of military populations and people with serious mental illness. Across these diverse areas of research, she reduces systematic biases and errors by using behavioral insights in survey design, developing flexible modular software programs for data management, and formalizing best practices for workflows and analysis.

Prior to joining Mathematica in 2015, Keshaviah served as a lead statistician at the Dana-Farber Cancer Institute, where she analyzed a pivotal breast cancer treatment trial that had international impact on patient management decisions; was a bioinformatics specialist at the Massachusetts General Hospital’s Department of Psychiatry, contributing to the latest version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); and was a 2006–2007 Fulbright fellow to India. Her work has been widely published in journals such as the New England Journal of Medicine, JAMA Psychiatry, and Envirometrics. Keshaviah holds a Master’s degree in biostatistics from the Harvard School of Public Health.

Key Projects
  • Health Care Surveys: Analysis and Presentation of Findings

    Mathematica is working with the Defense Health Agency to facilitate the implementation of health care beneficiary surveys, providing various support services, including sample and questionnaire design, reporting and research, weighting for nonresponse, data analysis, database construction, and documentation....

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